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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM1
All Species:
23.94
Human Site:
S591
Identified Species:
43.89
UniProt:
O95202
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95202
NP_036450.1
739
83354
S591
Q
E
I
K
K
E
L
S
K
T
G
E
E
K
Y
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
P332
L
H
L
K
E
N
V
P
P
S
L
L
L
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545925
741
83362
S592
Q
E
I
K
K
E
L
S
K
T
G
E
E
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2I0
738
82970
S590
Q
E
I
K
K
E
L
S
K
T
G
E
E
K
Y
Rat
Rattus norvegicus
Q5XIN6
739
83041
S590
Q
E
I
K
K
E
L
S
K
T
G
D
E
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516696
577
64046
P465
P
L
G
P
V
H
S
P
S
G
G
E
N
V
V
Chicken
Gallus gallus
Q5ZK33
752
85831
S602
L
Q
E
I
K
E
L
S
K
A
G
Q
E
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
S606
E
E
I
K
R
E
L
S
K
T
G
Q
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
V605
D
V
E
E
L
R
E
V
R
Q
V
V
K
E
P
Honey Bee
Apis mellifera
XP_624231
764
87758
S587
V
K
I
D
E
L
I
S
A
I
K
K
M
Q
S
Nematode Worm
Caenorhab. elegans
NP_506381
784
88704
E541
E
H
K
E
D
L
M
E
I
N
S
L
D
G
A
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
E432
R
A
M
G
V
P
L
E
R
L
K
S
Q
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08179
573
64987
T461
K
E
S
V
I
A
T
T
A
S
A
V
T
P
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
N.A.
85.8
N.A.
83.9
83.6
N.A.
55
73.5
N.A.
63.5
N.A.
30.3
34.1
35.2
20.4
Protein Similarity:
100
46.9
N.A.
91.3
N.A.
89.1
89
N.A.
62.2
83.9
N.A.
78.7
N.A.
46
56.6
56.6
38.5
P-Site Identity:
100
6.6
N.A.
93.3
N.A.
100
93.3
N.A.
13.3
46.6
N.A.
73.3
N.A.
0
13.3
0
6.6
P-Site Similarity:
100
33.3
N.A.
93.3
N.A.
100
100
N.A.
13.3
66.6
N.A.
93.3
N.A.
26.6
46.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
16
8
8
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
0
0
0
0
0
8
8
0
0
% D
% Glu:
16
47
16
16
16
47
8
16
0
0
0
31
47
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
8
54
0
0
8
0
% G
% His:
0
16
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
47
8
8
0
8
0
8
8
0
0
0
8
0
% I
% Lys:
8
8
8
47
39
0
0
0
47
0
16
8
8
31
8
% K
% Leu:
16
8
8
0
8
16
54
0
0
8
8
16
8
16
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% N
% Pro:
8
0
0
8
0
8
0
16
8
0
0
0
0
8
8
% P
% Gln:
31
8
0
0
0
0
0
0
0
8
0
16
8
8
0
% Q
% Arg:
8
0
0
0
8
8
0
0
16
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
54
8
16
8
8
0
0
24
% S
% Thr:
0
0
0
0
0
0
8
8
0
39
0
0
8
0
0
% T
% Val:
8
8
0
8
16
0
8
8
0
0
8
16
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _